CIED Infections & High Risk Patients

 

 

Bacterial infection is responsible for the majority of CIED complications...

and is on the rise

  • Increase in admissions for CIED infection is 5-fold the increase in CIED implantations1,2
  • Increased rate of infection likely due to2:        
    • More patient comorbidities     
    • Longer procedures          
    • More resistant S aureus and coagulase (-) Staphylococcus species (eg, S epidermidis)

 

Odds ratio for developing a CIED Infection3-7

Patient Characteristics, medications, and procedure characteristics significantly increase the risks

 

* Early Reintervention: new procedure to manage non-infectious complication before discharge

** Device Replacement/Revision: generator exchange or lead-related procedure involving opening the device pocket

*** Corticosteriod Use: >20mg ≥ 1 month in preceding year  

  1. Voigt et al. J Amer Coll Cardiol. 2006;48(3):590-591.  
  2. Voigt et al. PACE 2010;33(4):414-419.
  3. Klug D et al. Circulation 2007;116(12):1349-1355.
  4. Lekkerkerker JC et al. Heart 2009;95(9):715-720.
  5. Margey R et al. Europace 2010;12(1):64-70.
  6. Sohail MR et al. Clin Infect Dis. 2007;45(2):166-173.
  7. Bloom H et al. Pacing Clinical Electrophysiology 2006;29(2):142-145.